Senior Scientist in Single-Cell Assay Development in Pleasanton

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Job DescriptionJob DescriptionSalary:

Were looking for a Senior Scientist in Single-Cell Assay Development to help pioneer and validate novel approaches to scalable single-cell analysis. Youll be instrumental in designing, optimizing, and validating robust single-cell workflowsfrom concept to product. As an early team member, you'll shape both the scientific direction and the culture of the R&D team, helping establish a lean, high-performing, and high-output environment.

Key Responsibilities

• Lead the development of novel single-cell assays (e.g., scRNAseq, scDNAseq, multi-omic) tailored to CS Genetics proprietary platform.
• Design and execute experiments for assay optimization, troubleshooting, and validation using DOE and data-driven approaches.
• Collaborate across teams (Molecular Biology, Automation, Computational Biology) to integrate chemistry, workflow, and software into unified products.
• Establish best practices in lab execution, documentation, and data integrity to ensure reproducibility and quality.
• Build scalable protocols and documentation to support eventual tech transfer to manufacturing.
• Help shape team culture, workflows, and scientific strategy in a startup environment that values autonomy, speed, and rigor.
• Mentor junior scientists and contribute to recruiting efforts as the team grows.

Qualifications

• PhD in Molecular Biology, Analytical Chemistry, Biochemistry, or related field (or MS + 5+ years of hands-on experience).
• 37 years of industry or advanced academic experience developing single-cell genomics assays.
• Deep understanding of molecular biology principals and practice, nucleic acid chemistry, and NGS workflows.
• Strong bench skills in molecular biology (e.g., RT, ligation, tagmentation, amplification).
• Experience with assay optimization using DOE/statistical design.
• Familiarity with lab automation and high-throughput sample handling.
• Experience culturing mammalian cells
• Comfortable working in a fast-paced, evolving startup; capable of switching between high-level strategy and hands-on execution.
• Strong communication and organizational skills; commitment to quality and innovation.
• Experience with basic processing and analysis of single cell data is a plus

What We Offer

• A chance to build something truly transformative from the ground up.
• High ownership and autonomy in a fast-moving environment.
• Opportunities to shape company direction and culture.
• Competitive salary, equity, and benefits.

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