Senior Scientist, Process Development (Downstream)

Job DescriptionJob Description

Matica Biotechnology is at the forefront of biopharmaceutical research and development. The Matica Bio team brings an average of 15 years of cell and viral vector manufacturing experience to the development and manufacture of advanced therapy products. At our purpose-built GMP facility in College Station, Texas, we provide rapid development and scale-up of cell and gene therapies, vaccines, and Oncolytics meeting worldwide regulatory compliance.

The true value of a CDMO is determined by the quality of its people. Matica Bio consists of a dedicated team of experts. We’re a cell and gene therapy CDMO powered by people, and our people provide real benefits to the quality, safety and speed of the cell and gene therapy development pathway. Our inventive thinking and foresight help us strategize the best path to take therapies from the lab to the market. Come join our dedicated team and Make it Happen With Matica Bio!

Position Opportunity:

We seek to provide industry leading products and services with the goal to bring lifesaving and life altering therapies to patients worldwide. To achieve this goal, we strive to create the most effective and efficient processes possible to fulfill the promise of Gene and cell therapies.

The Senior Scientist I Downstream Process Development will lead activities within a downstream process development team to provide designs of experiments, scheduling, scale-up/down activities, formulation, technology transfer, characterization of downstream processes to produce novel therapeutic products. Excellent collaboration skills with stake holders inside and outside of the company and must be able to communicate project updates orally and through written presentations to both clients and management. This role will be expected to be a teacher and mentor for junior scientists through training and coaching. This position is in the Bryan-College Station area and the expectation is to be on site five business days a week or as required.

How you will make an impact:

Specific responsibilities include, but are not limited to:

• Identify, design, execute and analyze experimental protocols and present results to senior leadership, clients, and team members.
• Ensure all tasks performed in the lab are completed with safety being a priority.
• Authoring and revision of: SOPs, data presentations, study designs, protocols, and reports.
• Assess manufacturing processes supplied by client companies for suitability for GMP manufacture and identify any scale-up requirements/issues.
• Assist in the technology transfer process to enable clinical manufacture, using novel processes, within the GMP environment. This will require collaboration with the manufacturing team providing technical assistance as the subject matter expert.
• Operate and maintain a variety of lab equipment including but not limited to automated cell counters, bio-analyzers, microscopes, pumps, chromatography and TFF skids, scales, tubing welders/sealers and pH/conductivity meters.
• Serve as a subject matter expert for all downstream processes and closely collaborate with the upstream process development team.
• Utilize required excellent communication skills for collaboration across all company functions and client interfacing meetings.
• Represent the process development department and Matica through webinars, at conferences or other business-related gatherings.

As a future Matican You Bring:

Education

A minimum of a bachelor’s degree in a scientific discipline e.g., Biology, biochemistry, Virology, or equivalent.

Experience

• 8+ years industry experience in a Process Development role or a combination of development and cGMP manufacturing with a bachelor’s degree. Experience working in a cGMP environment, in the biotech industry. Consideration will be given to relevancy and quality of the job experience.
• 6+ years industry experience in a Process Development role or a combination of development and cGMP manufacturing with master’s degree or Ph.D. Experience working in a cGMP environment, in the biotech industry. Consideration will be given to relevancy and quality of the job experience.

Knowledge and Skills

• Ability to provide designs of experiments, scheduling, scale-up/down activities, formulation, technology transfer, characterization of downstream processes
• Ability to assess manufacturing processes supplied by client companies for GMP manufacture suitability
• Ability to teach/mentor junior scientists through training and coaching
• Excellent working knowledge of lab equipment including but not limited to automated cell counters, bio-analyzers, microscopes, pumps, chromatography and TFF skids, scales, tubing welders/sealers and pH/conductivity meters.
• Knowledge and ability of Technology Transfer Process
• Ability to revise documents such as SOPs, presentations, study designs, protocols, reports
• Ability to serve as a subject matter expert for all downstream processes and closely collaborate with the upstream process development team
• Collaborative team player
• Attention to detail
• Ability to wear appropriate PPE
• Excellent verbal and written communication skills
• Integrity, discretion, and confidentiality
• Computer software skills, organization, record keeping and planning
• Ability to maintain clean room facilities

Qualities & Attitude

• Strong work ethic, proactive, and self-motivated.
• Strong collaborator within a team and across departments.
• Dedication to continual learning and sharing of knowledge.

Competencies we look for:

Commitment to Excellence, Problem Solving/Decision Making/Analytical Thinking, Communication Skills, Teamwork/Cooperation/Supportiveness, Flexibility/Adaptability, Initiative/Taking Ownership, Focus on Safety, Ethical/Trustworthiness, Work Ethic/Reliability, Thoroughness, Customer Service

We Value:

Matica’s Values are at the forefront of everything we do, our culture, and the decisions we make.

• Start with Safety & Quality and Commit to Delivering Life Altering Therapies
• Choose the Path of Openness, Honesty, and Integrity
• Nurture Our to Enable Our Collective Success
• Learn Continuously to Ensure Our Value and Relevance