Research Scientist - mRNA Process Development in Reutlingen
Energy Jobline is the largest and fastest growing global Energy Job Board and Energy Hub. We have an audience reach of over 7 million energy professionals, 400,000+ monthly advertised global energy and engineering jobs, and work with the leading energy companies worldwide.
We focus on the Oil & Gas, Renewables, Engineering, Power, and Nuclear markets as well as emerging technologies in EV, Battery, and Fusion. We are committed to ensuring that we offer the most exciting career opportunities from around the world for our jobseekers.
Job Description
Accountability Cluster
Major Activities / Tasks
Development and Optimization of mRNA Manufacturing Processes
- Design, plan, and execute experiments to achieve robust, scalable processes for
- IVT,
- enzymatic treatments,
- purification
Execution of Relevant Analytical Methods for Process Evaluation
- Perform and supervise analytical tests to assess process performance.
- HPLC
- UV spectroscopy
- gel electrophoresis
- mRNA integrity/purity assays
Data Analysis and Interpretation for Process Improvement
- Analyse experimental results
- apply statistical methods
- provide recommendations to enhance process performance and product quality.
Preparation of Technical Documentation
- To capture process knowledge and ensure traceability write
- protocols
- study reports
- development summaries
Product & Process Robustness
- Perform product and process robustness analysis for improved mRNA/formulation CMC processes
- Calculation of COGS at various scales
- Provide technical support in improving Facility and Process Robustness also after process transfer for GMP manufacturing
Collaboration in Cross-Functional Project Teams
- Work with Analytical Development, Quality, and Manufacturing teams to ensure processes are transferable and compliant with GMP requirements
Support of Technology Transfer to GMP Manufacturing
- Participate in new product development for mRNA products as part of cross-functional project team
- Act as receiving party for in-licensed CMC processes and analytical methods
- Participate in transferring developed processes to manufacturing facilities, providing technical guidance and troubleshooting as needed
Educational qualifications:
Master’s or PhD in Biochemistry, Molecular Biology, Biotechnology, Chemical Engineering, or related field.
Relevant experience:
- 5+ years of industry experience in mRNA process development, bioprocess engineering, or mRNA manufacturing.
- Strong hands-on experience with in vitro transcription (IVT), mRNA purification techniques, and tangential flow filtration (TFF).
- Solid understanding of mRNA handling, enzymatic processing, and formulation strategies.
- Proficiency in data analysis, scientific writing, and presentation of technical findings.
- Quick learner with curiosity to challenge status quo and find innovative solutions
- Ability to document and communicate effectively in English; German skills are a plus
Educational qualifications:
Master’s or PhD in Biochemistry, Molecular Biology, Biotechnology, Chemical Engineering, or related field.
Relevant experience:
- 5+ years of industry experience in mRNA process development, bioprocess engineering, or mRNA manufacturing.
- Strong hands-on experience with in vitro transcription (IVT), mRNA purification techniques, and tangential flow filtration (TFF).
- Solid understanding of mRNA handling, enzymatic processing, and formulation strategies.
- Proficiency in data analysis, scientific writing, and presentation of technical findings.
- Quick learner with curiosity to challenge status quo and find innovative solutions
- Ability to document and communicate effectively in English; German skills are a plus
If you are interested in applying for this job please press the Apply Button and follow the application process. Energy Jobline wishes you the very best of luck in your next career move.