Process Associate - Analytical Development and Bioconjugation in Bethesda
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Job DescriptionJob Description
Workforce Genetics is currently seeking an experienced Process Associate specializing in antibody-drug conjugates.
The core responsibilities will be focused on three key areas:
Analytical Development
• Conduct analytical testing of bioconjugates, including ADCs, using techniques such as HPLC, LC-MS, UV-Vis, CE, and ELISA.
• Develop, optimize, and qualify analytical methods for characterization and release testing.
• Assist in method transfer, validation, and troubleshooting of analytical techniques.
• Maintain detailed and accurate records of experimental data in lab notebooks.
Bioconjugation Support
• Perform bioconjugation reactions, including linker-payload conjugation to antibodies.
• Assist in process optimization for conjugation efficiency, stability, and scalability.
• Conduct purification of conjugates using chromatography and filtration techniques.
• Collaborate with cross-functional teams to support process development and technology transfer.
QA and Documentation
• Ensure compliance with GLP/GMP guidelines, safety protocols, and regulatory requirements.
• Prepare reports, presentations, and documentation for internal and external stakeholders.
• Support equipment calibration, maintenance, and troubleshooting.
• Participate in team meetings, contribute to problem-solving discussions, and suggest process improvements.
Experience:
• Bachelor’s or Master’s degree in Biochemistry, Chemistry, Pharmaceutical Sciences, or a related field.
• 1 + years of experience in analytical development, bioconjugation, or a related field.
• Hands-on experience with analytical techniques such as HPLC, LC-MS, UV-Vis, and CE.
• Knowledge of bioconjugation chemistry and protein purification techniques.
• Experience with ADCs, linker-payload conjugation, or related bioconjugation technologies.
• Familiarity with GMP/GLP compliance and regulatory guidelines.
• Experience with data analysis tools such as Empower, MassLynx, or other chromatography software.
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