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Principal ML Engineer

Job Description

Principal ML Engineer

Health Tech Start-Up (AI-first transformation)

Manchester (hybrid)


Join a pioneering health tech start-up backed by a £20m Series A investment, already generating seven-figure ARR. We’re embarking on an ambitious journey to transform our industry-leading health platform into an AI-first solution, and we're seeking a Principal ML Engineer to lead this critical transformation from 0 to 1.


As our first dedicated ML hire, you’ll shape the future of our AI capabilities. You’ll lead hands-on development, from architecture through to deployment, integrating advanced machine learning models directly into our existing product. You'll collaborate closely with a talented engineering team of around 20 engineers, influencing both strategy and technical execution.


What you'll do:

  • Architect, design, and deploy scalable ML solutions from scratch.
  • Embed advanced AI capabilities deeply into our existing health tech platform.
  • Work hands-on, from model training to deployment and integration.
  • Influence technical strategy, establishing ML best practices across the team.
  • Collaborate closely with cross-functional teams to deliver real user value.


Who you are:

  • Experienced software engineer with a proven track record delivering robust production systems (front-end or back-end).
  • Demonstrable expertise in machine learning, with practical experience building and deploying ML models at scale.
  • Adept at working independently and taking ownership of large technical challenges.
  • Passionate about transforming products with AI and driving genuine innovation.
  • Excited by the prospect of being the first ML hire, with significant scope for impact and career growth.


This is a unique opportunity to make a direct and significant impact in a company at a pivotal moment. If you’re looking for a high-autonomy role with meaningful equity upside in a purpose-driven health tech start-up, we’d love to hear from you.

Principal ML Engineer

Manchester, UK
Full time

Published on 07/04/2025

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